6. Enantioselective Palladium-Catalyzed Allylic Substitution with Sulfur-Containing Oxazoline Ligands
Tetrahedron-Asymmetry 1993, 4, 1785-1788
Frost, C. G.; Williams, J. M. J.
Enantiomerically pure sulfur/nitrogen ligands have been prepared in one step from amino alcohols and 2-(methylthio)benzonitrile. We have successfully employed these ligands for enantioselective palladium catalysed allylic substitution, with asymmetric induction of up to 80% ee