5. Asymmetric Palladium-Catalyzed Allylic Substitution Using Phosphorus-Containing Oxazoline Ligands
Tetrahedron Letters 1993, 34, 3149-3150
Dawson, G. J.; Frost, C. G.; Williams, J. M. J.
A series of new phosphorus-containing oxazoline ligands has been developed. The use of these ligands for asymmetric palladium catalysed allylic substitution of 1,3-diphenylprop-2-enyl-1-acetate 12 with the sodium salt of dimethylmalonate has been achieved with 90 - 94% ee and 88 - 99% yield