4.10 AMS multiple symbols

$$\iint\limits_1^2,  
\sum_{\substack{p_1p_2\cdots p_{n}\\p_i \text{is prime}}}$$
\[ \iint \limits _1^2, \sum _{\substack {p_1p_2\cdots p_{n}\\ p_ i \text {is prime}}} \]