Ian Henderson WILLIAMS
I
have over 30 years experience in the application of computational methods to
the study of problems of chemical and biochemical reactivity, with particular
focus upon the transition state, environmental effects on mechanisms, the origins
of catalysis, and the interpretation of kinetic isotope effects.
Higher
Education:
1971-74
1974-77
Academic
Positions:
1977-78
1978-80
1980-85
1985-89
1989-91
1991-94
1995-
Professional
Memberships:
Fellow of the Royal Society of Chemistry and Chartered
Chemist
American Chemical Society
World Association of Theoretically Oriented Chemists
Selected
Recent Research Grants:
2002 £112K EPSRC ROPA:
Computational investigation of vibrational entropy in enzymatic catalysis
2003 £60K EPSRC/Johnson
Matthey: Computational modelling of catalytic processes
2004 £110K CEC Marie Curie: Can QM/MM
calculations reproduce experimental isotope effects?
2005 £261K BBSRC: Computational model for sialidase and sialosyltransferase
mechanism
2006 £260K EPSRC: A computational framework for interpretation of kinetic
isotope effects for organic reactions in solution
2007 £17K Mizutani Foundation for Glycoscience: The molecular basis of
human O-GlcNAse catalysis: theory and experiment
Current
Teaching and Administrative Responsibilities:
Teaching of physical organic chemistry to all Years of BSc and MChem
Chair of Natural Sciences Degree Programmes
Faculty of Science Executive Committee and Board of Studies
Recent
External Professional Duties:
Chair of RSC
Theoretical Chemistry Group Committee
EPSRC National Service for
Computational Chemistry Software Management Committee
Invited international conference
lectures (since 2003):
2003 International Isotope Effects Conference,
Uppsala, Sweden;
7th Latin
American Conference on Physical Organic Chemistry,
2004 227th American
Chemical Society National Meeting,
87th
Canadian Chemistry Conference,
228th
American Chemical Society National Meeting,
MGMS International Meeting:
Towards Accurate Calculation of Biomolecular Recognition & Reactivity,
2005 230th American
Chemical Society National Meeting,
eChemInfo Symposium on
Computational Quantum Biochemistry,
2006 FASEB Summer Research Conference on
Biological Methylation,
2007 Isotopes 2007,
2008 WATOC08,