Lewis Research Group

Synthetic Methodology & Natural Product Synthesis

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17.) "Photooxygenation of a Microbial Arene Oxidation Product and Regioselective Kornblum–DeLaMare Rearrangement. Total Synthesis of Zeylenols and Zeylenones”, Palframan, M. J.; Kociok-Köhn, G.; Lewis, S. E.* Chem. Eur. J., 2012, 18, 4766, 
doi:10.1002/chem.201104035

16.) “TRPA1 Mediates Spinal Antinociception Induced by Acetaminophen and the Cannabinoid Δ9-Tetrahydrocannabiorcol”, Andersson, D. A.; Gentry, C.; Alenmyr, L.; Killander, D.; Lewis, S. E.; Andersson, A.; Bucher, B.; Galzi, J.-L.; Sterner, O.; Bevan, S.; Högestätt, E. D.; Zygmunt, P. M. Nature Commun., 2011, 2, 551, doi:10.1038/ncomms1559

15.) “A Cobalt Complex of a Microbial Arene Oxidation Product”, van der Waals, D.; Pugh, T.; Ali Khan, M.; Stewart, A. J. W.; Johnson, A. L.; Lewis, S. E.*  Chem. Central J., 2011, 5, 80, doi:10.1186/1752-153X-5-80

14.) “Concise Synthesis of 1,4a-Bifunctionalised Decalin Building Blocks by C–H Activation of Decalin”, Uosis-Martin, M.; Mahon, M. F.; Yevglevskis, M.; Lewis, S. E.* Synlett, 2011, 2211–2213, doi: 10.1055/s-0030-1261184

13.) “Synthetic methods Part (II): oxidation and reduction methods”, Asghar, S. F.; Lewis, S. E.* Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2011, 107, 34–67, doi:10.1039/c1oc90012a

12.) “Total Synthesis of (+)-Grandifloracin by Iron Complexation of a Microbial Arene Oxidation Product”, Palframan, M. J.; Kociok-Köhn, G.; Lewis, S. E.* Org. Lett., 2011, 13, 3150–3153, doi:10.1021/ol201057r

11.) “Expanding the chiral pool: oxidation of meta-bromobenzoic acid by R. eutrophus B9 allows access to new reaction manifolds”, Griffen, J. A.; Le Coz, A. M.; Kociok-Köhn, G.; Ali Khan, M.; Stewart, A. J. W; Lewis, S. E.* Org. Biomol. Chem., 2011, 9, 3920–3928, doi:10.1039/c1ob05131h

10.) “Inosaminoacids: novel inositol–amino acid hybrid structures accessed by microbial arene oxidation”, Pilgrim, S.; Kociok-Köhn, G.; Lloyd, M. D.; Lewis, S. E.* Chem. Commun., 2011, 47 4799–4801  doi:10/1039/c1cc10643k

9.) “Accessing the antipodal series in microbial arene oxidation: a novel diene rearrangement induced by tricarbonyliron(0) complexation“, Ali Khan, M.; Lowe, J. P.; Johnson, A. L.; Stewart, A. J. W.; Lewis, S. E.* Chem. Commun., 2011, 47, 215–217 doi:10.1039/c0cc01169j

8.) “Iron(0)tricarbonyl Complexes of Microbially-Derived Cyclohexadiene Ligands Containing Quaternary Stereocenters”, Ali Khan, M.; Mahon, M. F.; Stewart, A. J. W.; Lewis, S. E.* Organometallics, 2010, 29, 199–204.   doi:10.1021/om9009069

7.) “Transannular decarboxylative Claisen rearrangement reactions for the synthesis of sulfur-substituted vinylcyclopropanes”, Craig, D.*; Gore, S. J.; Lansdell, M. I.; Lewis, S. E.; Mayweg, A. V. M.; White, A. J. P. Chem. Commun., 2010, 46, 4991–4993.   
doi:10.1039/c0cc00976h

6.) “Synthesis and Characterisation of Novel Alkane-α,ω-diyl bis(silyl triflates)”, Baker, T.; Lewis, S. E.* Synth. Commun., 2010, 40, 2747–2752.    doi:10.1080/00397910903318724

5.) “Crystallographic rationalization of the reactivity and spectroscopic properties of (2R)-S-(2,5-dihydroxyphenyl)cysteine”, Kociok-Köhn, G.; Lewis, S. E.* Acta Cryst., 2010, C66, o187–o189.   doi:10.1107/S0108270110005780 

4.) “Synthetic methods: Part (ii) Oxidation and reduction methods”, Lewis, S. E.* Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2010, 106, 34–75.   doi:10.1039/b927087f

3.) “Synthetic methods: Part (ii) Oxidation and reduction methods”, Lewis, S. E.* Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2009, 105, 35–74.   doi:10.1039/b822050f

2.) “Decarboxylative Claisen rearrangements of diallyl 2-sulfonylmalonates: remarkable regioselectivity in the reaction of bifunctional substrates”, Craig, D.*; Lansdell, M.; Lewis, S. E. Tetrahedron Lett., 2007, 48, 7861–7864.  doi:10.1016/j.tetlet.2007.08.130 

1.) “Recent advances in the chemistry of macroline, sarpagine and ajmaline-related indole alkaloids”, Lewis, S. E.* Tetrahedron, 2006, 62, 8655–8681.  doi:10.1016/j.tet.2006.06.017