Lewis Research Group

Synthetic Methodology & Natural Product Synthesis

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Click here for the full publication list with graphical abstracts and hyperlinks to the full text (Word file)

 

 

Click on the DOIs to read the full text of each article.

 

 

36.) “Phosphorus-substituted azulenes accessed via direct Hafner reaction of a phosphino cyclopentadienide”, Gee, A. P.; Cosham, S. D.; Johnson, A. L.; Lewis, S. E.* Synlett, 2017, ASAPdoi:10.1055/s-0036-1589936

 

 

35.) “What difference does a thiophene make? Evaluation of a 4,4’-bis(thiophene) functionalised 2,2’-bipyridyl copper(I) complex in a dye-sensitized solar cell”, Wills, K. A.; Mandujano-Ramírez, H. A.; Merino, G.; Oskam, G.; Cowper, P.; Jones, M. D.*; Cameron, P. J.*; Lewis, S. E.*  Dyes and Pigments, 2016, 134, 419-426.  doi:10.1016/j.dyepig.2016.07.023   [Open-Access]

 

 

34.) “Asymmetric Dearomatization Under Enzymatic Conditions”, Lewis, S. E. in Asymmetric Dearomatization Reactions (You, S.-L. ed.) Wiley-VCH, 2016, pp 279–346.  doi:10.1002/9783527698479.ch12

 

 

33.) “Langmuir monolayers composed of single and double tail sulfobetaine lipids”, Hazell, G.; Gee, A. P.; Arnold, T.; Edler, K.*; Lewis, S. E.  J. Colloid Interface Sci., 2016, 474, 190-198.  doi:10.1016/j.jcis.2016.04.020   [Open-Access]

 

 

32.) “Azulenesulfonium Salts: Accessible, Stable and Versatile Reagents for Cross-Coupling”, Cowper, P.*; Jin, Y.; Turton, M. D.; Kociok-Köhn, G.; Lewis, S. E.* Angew. Chem. Int. Edn., 2016, 55, 2564-2568.  doi:10.1002/anie.201510666   [Open-Access]

 

 

31.) “Biotransformations of Arenes: An Overview”, Lewis, S. E. in Arene Chemistry: Reaction Mechanisms and Methods for Aromatic Compounds (Mortier, J. ed.) Wiley-VCH, 2015, pp 915–937.  doi:10.1002/9781118754887.ch32

 

 

30.) “Tricarbonyliron(0) complexes of bio-derived η4 cyclohexadiene ligands: An approach to

analogues of oseltamivir”, ten Broeke, M.; Ali Khan, M.; Kociok-Köhn, G.; Kann, N.; Lewis, S. E.* J. Organomet. Chem., 2015, doi:10.1016/j.jorganchem.2015.09.005   [Open-Access]

 

 

29.) “Cycloparaphenylenes and related nanohoops”, Lewis, S. E.* Chem. Soc. Rev., 2015, 44, 2221-2304.  doi:10.1039/c4cs00366g   [Open-Access]

 

 

28.) “Direct core functionalisation of naphthalenediimides by iridium catalysed C-H borylation”, Lyall, C. L.; Shotton, C. C.; Pérez-Salvia, M.; Pantoş, G. D.*; Lewis, S. E.* Chem. Commun., 2014, 50, 13837-13840,  doi:10.1039/c4cc06522k   [Open-Access]

 

 

27.) “C-H functionalization of sp3 centers with aluminum: a computational and mechanistic study of the Baddeley reaction of decalin”, Lyall,C. L.; Sato, M.; Uosis-Martin, M.; Asghar, S. F.; Jones, M. D.; Williams, I. H.*; Lewis, S. E.* J. Am. Chem. Soc., 2014, 136, 13745-13753, doi:10.1021/ja5062246   [Open-Access]

 

 

26.) “A new assay for rhamnolipid detection—important virulence factors of Pseudomonas aeruginosa”, Laabei, M.; Jamieson, W. D.; Lewis, S. E.; Diggle, S. P.; Jenkins, A. T. A.*  Appl. Microbiol. Biotech., 2014, 98, 7199-7209,   doi:10.1007/s00253-014-5904-3  

 

 

25.) “The Enone Motif of (+)-Grandifloracin is Not Essential for “Anti-Austerity” Antiproliferative Activity”, Ali Khan, M.; Wood, Pauline J.; Lamb-Guhren, N. M.; Caggiano, L.; Kociok-Köhn, G.; Tosh, D.; Lewis, S. E.* Bioorg. Med. Chem. Lett., 2014, 24, 2815-2819.  doi:10.1016/j.bmcl.2014.04.111   [Open-Access]

 

 

24.) “Applications of biocatalytic arene ipso,ortho cis-dihydroxylation in synthesis”,

Lewis, S. E.*  Chem. Commun., 2014, 50, 2821-2830.  doi:10.1039/c3cc49694e

 

 

23.) “Benzoate dioxygenase from Ralstonia eutropha B9 - unusual regiochemistry of dihydroxylation permits rapid access to novel chirons”, Griffen, J. A.; Kenwright, S. J.; Abou-Shehada, S.; Wharry, S.; Moody, T. S.*; Lewis, S. E.*  Org. Chem. Front., 2014, 1, 79-90.   doi:10.1039/c3qo00057e   [Open-Access]

 

 

22.) “Investigation of a copper(I) biquinoline complex for application in dye-sensitized

solar cells”, Wills, K. A.; Mandujano-Ramírez, H. J.; Merino, G.; Mattia, D.; Hewat, T.; Robertson, N.; Oskam, G.; Jones, M. D.; Lewis, S. E.; Cameron, P. J. RSC Advances, 20133, 23361-23369.  doi:10.1039/c3ra44936j

 

 

21.) “A Model System for the Synthesis of Complanadine Alkaloids by ‘Diverted Kondrat’eva’ Oxazole-Olefin Cycloaddition”, Uosis-Martin, M.; Pantoş, G. D.; Mahon, M. F.; Lewis, S. E.* J. Org. Chem., 2013, 78, 6253-6263.  doi:10.1021/jo401014n  

 

 

20.) “New Aminocyclitols with Quaternary Stereocentres via Acylnitroso Cycloaddition with an ipso,ortho-Arene Dihydrodiol”, Griffen, J. A.; White, J. C.; Kociok-Köhn, G.; Lloyd, M. D.; Wells, A.; Arnot, T. C.; Lewis, S. E.* Tetrahedron, 2013, 69, 5989-5997.  doi:10.1016/j.tet.2013.04.033   [Open-Access]

 

 

19.) “Aliphatic C-H Activation with Aluminium Trichloride-Acetyl Chloride: Expanding the Scope of the Baddeley Reaction for the Functionalisation of Saturated Hydrocarbons”, Lyall, C. L.; Uosis-Martin, M.; Lowe, J. P.; Mahon, M. F.; Pantoş, G. D.; Lewis, S. E.* Org. Biomol. Chem., 2013, 11, 1468-1475. doi:10.1039/c2ob26765a  **Front Cover Article**

 

 

18.) "Valuable New Cyclohexadiene Building Blocks via Cationic η5 Iron Carbonyl Complexes Derived from a Microbial Arene Oxidation Product”, Ali Khan, M.; Mahon, M. F.; Lowe, J. P.; Stewart, A. J. W.; Lewis, S. E.* Chem. Eur. J., 2012, 18, 13480-13493, doi:10.1002/chem.201202411

 

 

17.) "Photooxygenation of a Microbial Arene Oxidation Product and Regioselective Kornblum-DeLaMare Rearrangement. Total Synthesis of Zeylenols and Zeylenones”, Palframan, M. J.; Kociok-Köhn, G.; Lewis, S. E.* Chem. Eur. J., 2012, 18, 4766-4774,

doi:10.1002/chem.201104035

 

 

16.) “TRPA1 Mediates Spinal Antinociception Induced by Acetaminophen and the Cannabinoid Δ9-Tetrahydrocannabiorcol”, Andersson, D. A.; Gentry, C.; Alenmyr, L.; Killander, D.; Lewis, S. E.; Andersson, A.; Bucher, B.; Galzi, J.-L.; Sterner, O.; Bevan, S.; Högestätt, E. D.; Zygmunt, P. M. Nature Commun., 2011, 2, 551, doi:10.1038/ncomms1559

 

 

15.) “A Cobalt Complex of a Microbial Arene Oxidation Product”, van der Waals, D.; Pugh, T.; Ali Khan, M.; Stewart, A. J. W.; Johnson, A. L.; Lewis, S. E.*  Chem. Central J., 2011, 5, 80, doi:10.1186/1752-153X-5-80   [Open-Access]

 

 

14.) “Concise Synthesis of 1,4a-Bifunctionalised Decalin Building Blocks by C-H Activation of Decalin”, Uosis-Martin, M.; Mahon, M. F.; Yevglevskis, M.; Lewis, S. E.* Synlett, 2011, 2211-2213, doi: 10.1055/s-0030-1261184

 

 

13.) “Synthetic methods Part (II): oxidation and reduction methods”, Asghar, S. F.; Lewis, S. E.* Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2011, 107, 34-67, doi:10.1039/c1oc90012a

 

 

12.) “Total Synthesis of (+)-Grandifloracin by Iron Complexation of a Microbial Arene Oxidation Product”, Palframan, M. J.; Kociok-Köhn, G.; Lewis, S. E.* Org. Lett., 2011, 13, 3150-3153, doi:10.1021/ol201057r   [Open-Access]

 

 

11.) “Expanding the chiral pool: oxidation of meta-bromobenzoic acid by R. eutrophus B9 allows access to new reaction manifolds”, Griffen, J. A.; Le Coz, A. M.; Kociok-Köhn, G.; Ali Khan, M.; Stewart, A. J. W; Lewis, S. E.* Org. Biomol. Chem., 2011, 9, 3920-3928, doi:10.1039/c1ob05131h

 

 

10.) “Inosaminoacids: novel inositol-amino acid hybrid structures accessed by microbial arene oxidation”, Pilgrim, S.; Kociok-Köhn, G.; Lloyd, M. D.; Lewis, S. E.* Chem. Commun., 2011, 47 4799-4801  doi:10/1039/c1cc10643k

 

 

9.) “Accessing the antipodal series in microbial arene oxidation: a novel diene rearrangement induced by tricarbonyliron(0) complexation”, Ali Khan, M.; Lowe, J. P.; Johnson, A. L.; Stewart, A. J. W.; Lewis, S. E.* Chem. Commun., 2011, 47, 215-217 doi:10.1039/c0cc01169j

 

 

8.) “Iron(0)tricarbonyl Complexes of Microbially-Derived Cyclohexadiene Ligands Containing Quaternary Stereocenters”, Ali Khan, M.; Mahon, M. F.; Stewart, A. J. W.; Lewis, S. E.* Organometallics, 2010, 29, 199-204.   doi:10.1021/om9009069

 

 

7.) “Transannular decarboxylative Claisen rearrangement reactions for the synthesis of sulfur-substituted vinylcyclopropanes”, Craig, D.*; Gore, S. J.; Lansdell, M. I.; Lewis, S. E.; Mayweg, A. V. M.; White, A. J. P. Chem. Commun., 2010, 46, 4991-4993.  

doi:10.1039/c0cc00976h

 

 

6.) “Synthesis and Characterisation of Novel Alkane-α,ω-diyl bis(silyl triflates)”, Baker, T.; Lewis, S. E.* Synth. Commun., 2010, 40, 2747-2752.    doi:10.1080/00397910903318724

 

 

5.) “Crystallographic rationalization of the reactivity and spectroscopic properties of (2R)-S-(2,5-dihydroxyphenyl)cysteine”, Kociok-Köhn, G.; Lewis, S. E.* Acta Cryst., 2010, C66, o187-o189.   doi:10.1107/S0108270110005780

 

 

4.) “Synthetic methods: Part (ii) Oxidation and reduction methods”, Lewis, S. E.* Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2010, 106, 34-75.   doi:10.1039/b927087f

 

 

3.) “Synthetic methods: Part (ii) Oxidation and reduction methods”, Lewis, S. E.* Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2009, 105, 35-74.   doi:10.1039/b822050f

 

 

2.) “Decarboxylative Claisen rearrangements of diallyl 2-sulfonylmalonates: remarkable regioselectivity in the reaction of bifunctional substrates”, Craig, D.*; Lansdell, M.; Lewis, S. E. Tetrahedron Lett., 2007, 48, 7861-7864.  doi:10.1016/j.tetlet.2007.08.130 

 

 

1.)Recent advances in the chemistry of macroline, sarpagine and ajmaline-related indole alkaloids, Lewis, S. E.* Tetrahedron, 2006, 62, 8655-8681doi:10.1016/j.tet.2006.06.017