55. Switching stereoselectivity in rhodium-catalysed 1,4-additions: the asymmetric synthesis of 2-substituted pyrrolizidinones
Chemical Communications, 2006, 4389 - 4391
Jonathan D. Hargrave, Gerwyn Bish and Christopher G. Frost
he appropriate choice of organometallic nucleophile enables the straightforward preparation of different stereoisomers of 2-substituted pyrrolizidinones utilising the rhodium-catalysed 1,4-addition reaction.
