37. Synthesis of Functionalised Phenylalanines Using Rhodium Catalysis in Water
Advanced Synthesis & Catalysis 2003, 345, 353-355
Chapman, C. J.; Frost, C. G.
The efficient synthesis of substituted phenylalanine-type amino acids using a rhodium-catalysed, conjugate addition of arylboronic acids is described. The reactions are run in water and use a low loading (0.5 mol %) of rhodium catalyst.