53. Rhodium-Catalysed Addition of Organotrialkoxysilanes to -Substituted Acrylic Esters
Organic and Biomolecular Chemistry, 2006, 4, 3235 - 3241
Jonathan D. Hargrave, Jennifer Herbert, Gerwyn Bish and Christopher G. Frost
The cationic rhodium complex [Rh(cod)2][BF4] effectively catalyses the 1,4-addition of organotrialkoxysilanes to -substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and -amino acid derivatives.