University of Bath, Claverton Down, Bath BA2 7AY
Tel: +44 (0)1225 826132, Fax: +44 (0)1225 826894
Dr John Hubble
Reader in Biochemical Engineering
Introductory material
This material was developed to form part of our final year undergraduate bioseparations module. It is written to provide an introduction to the types of chromatography employed in bioseparations. The background to a number of models for performance evaluation is included.
Introduction as web page Adsorption
Download introduction as a Word 97 document Adword
(While reasonable care has been taken in the preparation of this material I cannot guarantee that it is error free. If you notice any mistakes, or feel additional material would be helpful please email me at J.Hubble@bath.ac.uk)
Adsorption models
As a result of our research interests in Affinity Adsorption I have written a number of programs based on different models of adsorption performance. These are based on different packages/programing environments and may be found following the links below.
ADCOL is the exception in that it is a relatively complete package that allows modelling of the Load/Wash/Elute stages of an adsorption cycle. ADCOL is a Visual BASIC package and can be downloaded as a ZIP file ADCOL. ADCOL is based on a simple model that treats an adsorption column as a series of well mixed tanks. The core routine is listed under the PowerBASIC link (lumped.bas).
Programs that require a high level programming language have been written in PowerBASIC. These can be found here
Spreadsheet models are written in Microsoft EXCEL and can be found here
EXCEL
Other models that allow fitting of experimental data to models are written for Scientist or Berkeley Madonna
Scientist files
